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KMID : 0377619890540050309
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Korean Jungang Medical Journal
1989 Volume.54 No. 5 p.309 ~ p.315
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Study for Serum Immunoglobulin Related to Tonsillectomy
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Abstract
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The palatine tonsils are located in entrance of digestive and upper respiratory tracts and they are generally accepted participate in protective, endocrinologic, hematopoietic, digestive function and vitamin production.
But recently, defense mechanism of tonsils is strongly accepted immunologically.
Authors observed serum immunoglobulin G,A,M,D and E level before and after 20 cases of tonsillectomy, and then compared with 10 cases of healthy individuals as a control in Department of Otolaryngology of Chunbuk National University Hospital During September 1988.
The immunoglobulin levels were measured with Radial Immunodiffusion Method, and clinic statistical analysis for achieved data was performed.
The results were followed;
1) In the tonsillectomy group, preoperative serum IgG was 1635.7 ± 795.7 (mg/dl), IgA was 191.4 ± 127.2 (mg/dl), IgM was 188.4 ± 77.8 (mg/dl), IgD was 10.0 ± 9.1 (mg/dl), IgE was 30.8 ± 26.3 (mg/dl), and post-operative serum IgG was 1205.0 ± 493.1 (mg/dl), IgA was 166.6 ± 105.4 (mg/dl), IgM was 196.0 ± 95.1 (mg/dl), IgD was 9.9 ± 9.3 (mg/dl), IgE was 88.2 ± 80.6 (mg/dl).
In the control group, serum IgG was 1598.1. ± 773.8 (mg/dl), IgA was 274.9 ± 165.6 (mg/dl), IgM was 189.8 ± 106.6 (mg/dl), IgD was 5.51 ± 5.11 (mg/dl), IgE was 49.85 ± 47.1 (mg/dl).
2) Pre-operative serum immunoglobulin levels in chronic tonsillitis patients showed no difference than in control group clinicosatistically.
3) Post-operative serum. immunoglobulin G, A, D levels were decreased but decrease of immunoglobulin A, D level was not clinicostatistically significant.
Post-operative serum immunoglobulin M, E level were elevated but elevation of immunoglobulin E was clinicostatistically significant post-operation serum immunoglobulin levels were similar to the levels of control group. But IgA level of control group was higher than that of post-operative group.
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